Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 4/20 | 0.72 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.72 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.72 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.72 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.72 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676414 | 0.90 | GRIN2D (0.68) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1557957 | 0.84 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL167788 | 0.84 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6021110 | 0.84 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9749886 | 0.81 | GRIN2D (0.69) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5059534 | 0.80 | GRIN2D (0.77) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13662562 | 0.80 | GRIN2D (0.67) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1207222 | 0.76 | GRIN2D (0.61) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8828049 | 0.76 | ALOX15 (0.71) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5059538 | 0.75 | GRIN2D (0.69) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595983-A | ANTAGONIST ACTION AT AMINO ACID RECEPTORS, ANTICONVULSANTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-01-21 | — | — | US | disclosed |
| US-5399693-A | Substituted piperazine-2-carboxylic acids and derivatives thereof | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-03-21 | — | — | US | disclosed |
| EP-0159889-B1 | 4-SUBSTITUTED PIPERAZINE-2-CARBOXYLIC ACIDS PROCESS AND PHARMACEUTICAL COMPOSITIONS | BTG INTERNATIONAL LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| EP-0159889-A2 | 4-Substituted piperazine-2-carboxylic acids process and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1985-10-30 | — | — | EP | disclosed |