Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.37 |
| ▸ | DDO | Q99489 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927156 | 0.82 | DAO (0.33) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL28746603 | 0.81 | DAO (0.30) | DAODDO | |
| SCHEMBL8828084 | 0.79 | GRIN2D (0.48) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8828079 | 0.78 | GRIN2D (0.53) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL3203267 | 0.74 | DAO (0.58) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL7740551 | 0.73 | PRKAG1 (0.43) | DAODDO | |
| SCHEMBL7739865 | 0.72 | GRIA1 (0.61) | GRIK1 | |
| SCHEMBL31378692 | 0.71 | GRIN2D (0.39) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL6927437 | 0.70 | CA1 (0.41) | — | |
| SCHEMBL8828102 | 0.70 | KDM4E (0.53) | DAODDOEIF4A3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646132-A | TREATING CEREBRAL ISCHEMIA | ADIR ET COMPAGNIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5536709-A | INHIBITORS OF HYPERACTIVATION OF EXCITATORY AMINO ACIDS | ADIR ET COMPAGNIE (FR) | 1996-07-16 | — | — | US | disclosed |