Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273247 | 0.83 | EIF4A3 (0.68) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423132 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31422910 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31422970 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL8500109 | 0.79 | KDM4E (0.63) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423115 | 0.79 | DAO (0.63) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL9398264 | 0.79 | EGLN1 (0.45) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31422856 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL14128774 | 0.79 | GRIA1 (0.53) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL8828077 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1GAAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646132-A | TREATING CEREBRAL ISCHEMIA | ADIR ET COMPAGNIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5536709-A | INHIBITORS OF HYPERACTIVATION OF EXCITATORY AMINO ACIDS | ADIR ET COMPAGNIE (FR) | 1996-07-16 | — | — | US | disclosed |