Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | IL6ST | P40189 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 8/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991055 | 0.92 | USP2 (0.39) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL7991050 | 0.92 | USP2 (0.39) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL8828126 | 0.89 | PPARA (0.40) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL974301 | 0.89 | KLK7 (0.43) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL2025733 | 0.89 | KLK7 (0.43) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL6448977 | 0.89 | KLK7 (0.43) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL8554608 | 0.89 | FAAH (0.40) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL8554605 | 0.89 | FAAH (0.40) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL6448978 | 0.89 | KLK7 (0.43) | PPARAIL6STPLA2G10PLA2G5NAAA | |
| SCHEMBL8011986 | 0.89 | PPARA (0.39) | PPARAIL6STPLA2G10PLA2G5NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618844-A | MATRIX METALLOPROTEINASE INHIBITOR | SANOFI S.A. (FR) | 1997-04-08 | — | — | US | disclosed |