Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452908 | 0.86 | LMNA (0.80) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL9687063 | 0.79 | LMNA (0.69) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL11119158 | 0.77 | LMNA (0.57) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL1392640 | 0.77 | LMNA (0.67) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL11035831 | 0.77 | LMNA (1.00) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL4122238 | 0.77 | LMNA (0.67) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL2152989 | 0.77 | LMNA (0.67) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL928226 | 0.77 | LMNA (0.67) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL928205 | 0.77 | LMNA (0.67) | LMNAKMT2AMEN1CYP1A2PDE3B | |
| SCHEMBL481916 | 0.77 | LMNA (0.67) | LMNAKMT2AMEN1CYP1A2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607953-A | ANTIISCHEMIC AGENTS | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0344577-B1 | Butenoic or propenoic acid derivatives | EISAI CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5382595-A | Antiischemic agents | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| US-5047417-A | Butenoic or propenoic acid derivatives | EISAI CO. LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| CN-1040366-A | Butenoic acid or acrylic acid derivative | EISAI CO LTD (JP) | 1990-03-14 | — | — | CN | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |