Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828251 | 1.00 | PAM (0.47) | PAMLMNANPC1RAB9ATP53 | |
| SCHEMBL6852522 | 0.83 | LMNA (0.40) | LMNANPC1RAB9ATP53POLB | |
| SCHEMBL6852515 | 0.83 | LMNA (0.40) | LMNANPC1RAB9ATP53POLB | |
| SCHEMBL9157074 | 0.81 | MKNK1 (0.52) | PAMLMNANPC1RAB9AMAPT | |
| SCHEMBL9157078 | 0.81 | MKNK1 (0.52) | PAMLMNANPC1RAB9AMAPT | |
| SCHEMBL6854142 | 0.75 | LMNA (0.43) | LMNANPC1RAB9ATP53POLB | |
| SCHEMBL7230008 | 0.75 | LMNA (0.48) | LMNANPC1RAB9ATP53POLB | |
| SCHEMBL2998855 | 0.75 | PAM (0.61) | PAMLMNANPC1RAB9ATP53 | |
| SCHEMBL2998851 | 0.75 | PAM (0.61) | PAMLMNANPC1RAB9ATP53 | |
| SCHEMBL1867087 | 0.73 | TP53 (0.54) | LMNANPC1RAB9ATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618502-A | PURIFICATION BY ELUTING THROUGH AN ANIONIC EXCHANGE RESIN | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1997-04-08 | — | — | US | disclosed |
| US-5607953-A | ANTIISCHEMIC AGENTS | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0344577-B1 | Butenoic or propenoic acid derivatives | EISAI CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0490128-B1 | Zirconium-hafnium production in a zero liquid discharge process | WESTINGHOUSE ELECTRIC CORP (US) | 1996-05-22 | — | — | EP | disclosed |
| US-5382595-A | Antiischemic agents | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0490128-A2 | Zirconium-hafnium production in a zero liquid discharge process | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5112493-A | Liquid chromatography, acidification, rotation and separation followed by reduction | WESTINGHOUSE ELECTRIC CORP. (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |