Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828318 | 0.89 | DRD3 (0.44) | DRD3DRD2CYP11B1CYP11B2GAA | |
| SCHEMBL8828195 | 0.88 | OPRM1 (0.44) | GAA | |
| SCHEMBL8828202 | 0.88 | DRD3 (0.41) | DRD3DRD2CYP11B1CYP11B2GAA | |
| Hydrochloric Acid SCHEMBL6368810 | 0.88 | DRD3 (0.41) | DRD3DRD2CYP11B1CYP11B2GAA | |
| SCHEMBL8828419 | 0.87 | MAOB (0.38) | DRD3DRD2 | |
| SCHEMBL8828168 | 0.87 | DRD3 (0.45) | MTNR1AMTNR1BDRD3DRD2 | |
| SCHEMBL9231352 | 0.87 | DRD3 (0.45) | DRD3DRD2CYP11B1CYP11B2GAA | |
| SCHEMBL9233122 | 0.86 | OPRM1 (0.42) | GAA | |
| SCHEMBL9155730 | 0.86 | DRD3 (0.42) | DRD3DRD2CYP11B1CYP11B2GAA | |
| SCHEMBL9160192 | 0.85 | CYP3A4 (0.38) | DRD3DRD2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607953-A | ANTIISCHEMIC AGENTS | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0344577-B1 | Butenoic or propenoic acid derivatives | EISAI CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5382595-A | Antiischemic agents | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |