Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798177 | 0.85 | TBXAS1 (0.38) | CYP4F2CYP4A11TBXAS1CYP2C19 | |
| SCHEMBL773974 | 0.81 | CYP2C19 (0.44) | CYP4F2CYP4A11TBXAS1TSHRCYP2C19 | |
| SCHEMBL774169 | 0.81 | CYP2C19 (0.44) | CYP4F2CYP4A11TBXAS1TSHRCYP2C19 | |
| SCHEMBL773583 | 0.80 | CYP4F2 (0.42) | CYP4F2CYP4A11TBXAS1 | |
| SCHEMBL774105 | 0.78 | CYP2C19 (0.46) | CYP4F2CYP4A11TBXAS1TSHRCYP2C19 | |
| SCHEMBL882520 | 0.78 | TBXAS1 (0.38) | CYP4F2CYP4A11TBXAS1CYP2C19 | |
| SCHEMBL15686684 | 0.78 | TBXAS1 (0.40) | CYP4F2CYP4A11TBXAS1CYP2C19 | |
| SCHEMBL797961 | 0.78 | CYP4F2 (0.69) | CYP4F2CYP4A11TBXAS1CYP2C19 | |
| SCHEMBL14704292 | 0.77 | L3MBTL1 (0.40) | CYP4F2CYP4A11TSHRTP53 | |
| SCHEMBL13010603 | 0.77 | CYP2C19 (0.45) | CYP4F2CYP4A11TSHRTP53CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040177-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA | KAREUS THERAPEUTICS, SA (CH) | 2012-03-29 | — | — | WO | disclosed |