SCHEMBL882841

SCHEMBL882841

CC(C)(C)OC(=O)C1(CCCCCCCCCCCCC2(N)CC2)CC1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.52
CYP4A11 Q02928 2/20 0.52
TDP1 Q9NUW8 1/20 0.33
P4HB P07237 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL798199 0.90 CYP4F2 (0.60) CYP4F2CYP4A11TDP1P4HB
SCHEMBL798441 0.90 CYP4F2 (0.60) CYP4F2CYP4A11TDP1P4HB
SCHEMBL797984 0.90 CYP4F2 (0.60) CYP4F2CYP4A11TDP1P4HB
SCHEMBL798227 0.90 CYP4F2 (0.60) CYP4F2CYP4A11TDP1P4HB
SCHEMBL25996655 0.85 CYP4F2 (0.68) CYP4F2CYP4A11TDP1P4HB
SCHEMBL516843 0.83 CYP4F2 (0.51) CYP4F2CYP4A11TDP1P4HB
SCHEMBL14892163 0.83 CYP4F2 (0.65) CYP4F2CYP4A11TDP1P4HB
SCHEMBL23971079 0.82 CYP4F2 (0.53) CYP4F2CYP4A11TDP1P4HB
SCHEMBL23971374 0.82 CYP4F2 (0.53) CYP4F2CYP4A11TDP1P4HB
SCHEMBL798231 0.82 CYP4F2 (0.53) CYP4F2CYP4A11TDP1P4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012040177-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA KAREUS THERAPEUTICS, SA (CH) 2012-03-29 WO disclosed
US-20120071528-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA KAREUS THERAPEUTICS, SA (CH) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071528-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA LIPC, PNLIP, LIPA CYP4F2 361/4885CYP4A11 66/4885TDP1 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.