Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027775 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL9028483 | 0.90 | DRD2 (0.64) | DRD2 | |
| Hydrochloric Acid SCHEMBL9028188 | 0.89 | DRD2 (0.65) | DRD2 | |
| SCHEMBL9027526 | 0.89 | DRD2 (0.64) | DRD2 | |
| Hydrochloric Acid SCHEMBL9027388 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL9028127 | 0.88 | DRD2 (0.63) | DRD2 | |
| SCHEMBL9027734 | 0.87 | ADRA1D (0.75) | — | |
| Hydrochloric Acid SCHEMBL9026670 | 0.87 | ADRA1D (0.74) | — | |
| SCHEMBL9027001 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL9028401 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711757-A1 | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists | F. Hoffmann-La Roche AG (CH) | 1996-05-15 | — | — | EP | claimed |
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0711757-A1 | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists | F. Hoffmann-La Roche AG (CH) | 1996-05-15 | — | — | EP | disclosed |