Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8828673 | 0.99 | ADRA1A (0.48) | ADRA1AHTR1AADRA1DADRA1BDRD2 | |
| SCHEMBL8828466 | 0.92 | AKR1C3 (0.48) | ADRA1AHTR1AADRA1DADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL8828702 | 0.91 | AKR1C3 (0.47) | ADRA1AHTR1AADRA1DADRA1BDRD2 | |
| SCHEMBL8828587 | 0.86 | HTR1A (0.48) | ADRA1AHTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8828668 | 0.85 | HTR1A (0.47) | ADRA1AHTR1ADRD2DRD4 | |
| SCHEMBL8828467 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL8828741 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL8828552 | 0.81 | ADRA1A (0.47) | ADRA1AHTR1AADRA1DADRA1BDRD2 | |
| SCHEMBL8828621 | 0.81 | USP2 (0.47) | ADRA1AHTR1AADRA1DADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL8828676 | 0.80 | USP2 (0.46) | ADRA1AHTR1AADRA1DADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |