Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12686079 | 0.80 | ERN1 (0.58) | ERN1TYR | |
| SCHEMBL3965396 | 0.79 | GABRA1 (0.57) | ERN1CA1CA2TYRGABRA1 | |
| SCHEMBL310863 | 0.79 | ERN1 (0.67) | ERN1CA1CA2TYRGABRA1 | |
| SCHEMBL29617422 | 0.79 | GABRA1 (0.57) | ERN1CA1CA2TYRGABRA1 | |
| SCHEMBL310578 | 0.78 | ERN1 (0.64) | ERN1CA1CA2TYRGABRA1 | |
| SCHEMBL10322298 | 0.78 | GABRA1 (0.64) | ERN1CA1CA2TYRGABRA1 | |
| SCHEMBL5419620 | 0.76 | GSR (0.44) | ERN1CA1CA2TYRGABRA1 | |
| SCHEMBL10809787 | 0.75 | ERN1 (0.41) | ERN1CA1CA2TYRGABRA1 | |
| SCHEMBL882961 | 0.75 | ERN1 (0.54) | ERN1CA1CA2ALDH1A1CYP1A2 | |
| SCHEMBL15922982 | 0.74 | GSR (0.42) | ERN1CA1CA2TYRGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040454-A2 | SYNTHESIS OF SUBSTITUTED SALICYLALDEHYDE DERIVATIVES | NOVOMER, INC. (US) | 2012-03-29 | — | — | WO | disclosed |