Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | ERN1 | O75460 | 3/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617422 | 1.00 | GABRA1 (0.57) | GABRA1GABRB2ERN1TYRFABP3 | |
| SCHEMBL20509047 | 0.82 | TYR (0.61) | GABRA1GABRB2ERN1TYRKDM4E | |
| SCHEMBL310863 | 0.81 | ERN1 (0.67) | GABRA1GABRB2ERN1TYRCA1 | |
| SCHEMBL26229436 | 0.79 | ERN1 (0.58) | GABRA1GABRB2ERN1TYRKDM4E | |
| SCHEMBL310578 | 0.79 | ERN1 (0.64) | GABRA1GABRB2ERN1TYRCA1 | |
| SCHEMBL10322298 | 0.79 | GABRA1 (0.64) | GABRA1GABRB2ERN1TYRCA1 | |
| SCHEMBL882866 | 0.79 | ERN1 (0.44) | GABRA1GABRB2ERN1TYRCA1 | |
| SCHEMBL94533 | 0.79 | GABRA1 (0.77) | GABRA1GABRB2FABP3FABP4FABP5 | |
| SCHEMBL11249537 | 0.78 | GABRA1 (0.53) | GABRA1GABRB2TYRFABP3FABP4 | |
| SCHEMBL11249533 | 0.78 | GABRA1 (0.53) | GABRA1GABRB2TYRFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101514212-B | Synthetic method of pyridine-2''amino-2'-hydroxybenzene methanol phenylcarbinol boric acid ester compound | UNIV LIAONING | 2011-11-09 | — | — | CN | claimed |
| CN-1228356-C | Norbornene polymerization catalyst system and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2005-11-23 | — | — | CN | claimed |
| CN-1200017-C | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2005-05-04 | — | — | CN | claimed |
| CN-1167720-C | Polymeric catalyst system of norbornaene and its preparing process | 中国科学院化学研究所 | 2004-09-22 | — | — | CN | claimed |
| CN-1139606-C | Norbornene catalytic system and its preparation method and application | 中国科学院化学研究所 | 2004-02-25 | — | — | CN | claimed |
| CN-1394685-A | Norbornene catalytic system and its preparation method and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-02-05 | — | — | CN | claimed |
| CN-1390867-A | Polymeric catalyst system of norbornaene and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-15 | — | — | CN | claimed |
| CN-1388139-A | Norbornene polymerization catalyst system and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-01 | — | — | CN | claimed |
| CN-1388140-A | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-01 | — | — | CN | claimed |
| CN-109054011-B | Schiff base cobalt compound, preparation method thereof and preparation method of polycarbonate | 中国科学院长春应用化学研究所 | 2021-01-08 | — | — | CN | disclosed |
| CN-103396457-B | The preparation method of a kind of Schiff's base cobalt compound, its preparation method and polycarbonate | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-103396457-A | Schiff base cobalt compound and preparation method thereof as well as preparation method of polycarbonate | CHANGCHUN APPLIED CHEMISTRY | 2013-11-20 | — | — | CN | disclosed |
| EP-1992630-B1 | Covalently fixed non-metallocenes, method for the production thereof and their use for polymerizing olefins | TICONA GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| CN-101514212-B | Synthetic method of pyridine-2''amino-2'-hydroxybenzene methanol phenylcarbinol boric acid ester compound | UNIV LIAONING | 2011-11-09 | — | — | CN | disclosed |
| US-5849742-A | Compounds for the treament of disorders related to vasculogenesis and/or angiogenesis | SUGEN INC. (US) | 1998-12-15 | — | — | US | disclosed |
| US-5792771-A | FOR TREATING TUMORS, VASCULAR SYSTEM DISORDERS, DIABETES, DIABETIC RETINOPATHY, RHEUMATOID ARTHRITIS AND HEMANGIOMA | SUGEN, INC. (US) | 1998-08-11 | — | — | US | disclosed |
| US-5763441-A | ADMINISTERING TO THE PATIENT SUFFERING FROM DIABETES, GLIOMA, HEMANGIOMA, KAPOSI'S SARCOMA, OVARIAN/BREAST/PANCREATIC/COLON AND PROSTATE CANCER A BENZO(G)QUINOXALINE COMPOUNDS | SUGEN, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5712395-A | BENZO(G)QUINOXALINE | YISSUM RESEARCH DEVELOPMENT CORP. (IL) | 1998-01-27 | — | — | US | disclosed |
| EP-0748219-A1 | COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS | Sugen, Inc. (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995021613-A1 | COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS | SUGEN, INC. (US) | 1995-08-17 | — | — | WO | disclosed |