Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 10/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828471 | 0.85 | KCNQ2 (0.51) | KCNQ2KCNQ3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4078674 | 0.78 | GAA (0.44) | KCNQ2KCNQ3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5104674 | 0.78 | NPSR1 (0.63) | KCNQ2GLATSHRMAPTALDH1A1 | |
| SCHEMBL3070911 | 0.76 | NPSR1 (0.65) | KCNQ2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7833448 | 0.76 | CHEK1 (0.50) | SMN1; SMN2NPSR1GAAMEN1KMT2A | |
| SCHEMBL8828431 | 0.75 | CYP2D6 (0.48) | CYP2D6CYP2C9TSHRMAPTALDH1A1 | |
| SCHEMBL9991702 | 0.70 | TP53 (0.43) | TSHRMAPTPOLB | |
| SCHEMBL6506614 | 0.69 | DRD2 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL8828398 | 0.69 | KMT2A (0.56) | MAPTALDH1A1SMN1; SMN2NPSR1GAA | |
| SCHEMBL28718374 | 0.67 | CHRNA7 (0.55) | TSHRMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |