Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5104674 | 0.80 | NPSR1 (0.63) | GAASMN1; SMN2NPSR1MAPTKMT2A | |
| SCHEMBL8828664 | 0.78 | KCNQ2 (0.47) | GAASMN1; SMN2NPSR1MAPTKMT2A | |
| SCHEMBL3070911 | 0.78 | NPSR1 (0.65) | GAASMN1; SMN2NPSR1MAPTKMT2A | |
| SCHEMBL7833448 | 0.78 | CHEK1 (0.50) | GAASMN1; SMN2NPSR1KMT2AL3MBTL1 | |
| SCHEMBL8828431 | 0.74 | CYP2D6 (0.48) | GAASMN1; SMN2NPSR1MAPTKMT2A | |
| SCHEMBL18701666 | 0.67 | ALDH1A1 (0.62) | GAASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL6517475 | 0.66 | JAK2 (0.49) | MAPTL3MBTL1 | |
| SCHEMBL29955558 | 0.66 | JAK2 (0.49) | MAPTL3MBTL1 | |
| SCHEMBL9994315 | 0.65 | PDK2 (0.50) | GAASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL3846828 | 0.65 | PTGS1 (0.58) | MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016057-A1 | C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007123516-A1 | C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-11-01 | — | — | WO | disclosed |