Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927716 | 0.85 | HSD17B3 (0.40) | MEN1KMT2AALDH1A1HSD17B3USP2 | |
| SCHEMBL9330383 | 0.84 | MEN1 (0.47) | MEN1KMT2AALDH1A1HSD17B3USP2 | |
| Iodide SCHEMBL1780078 | 0.83 | HSD17B3 (0.39) | MEN1KMT2AALDH1A1HSD17B3USP2 | |
| Iodide SCHEMBL2821259 | 0.83 | HSD17B3 (0.39) | MEN1KMT2AALDH1A1HSD17B3USP2 | |
| Hydrochloric Acid SCHEMBL30935728 | 0.83 | MEN1 (0.40) | MEN1KMT2AALDH1A1HSD17B3USP2 | |
| Iodide SCHEMBL1780085 | 0.83 | HSD17B3 (0.39) | MEN1KMT2AALDH1A1HSD17B3USP2 | |
| Bromide SCHEMBL9328394 | 0.82 | MEN1 (0.46) | MEN1KMT2AALDH1A1HSD17B3USP2 | |
| SCHEMBL29767838 | 0.82 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1L3MBTL1USP2 | |
| Bromide SCHEMBL29283498 | 0.79 | CYP1A2 (0.40) | MEN1KMT2AALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL19411236 | 0.78 | HTR2A (0.46) | MEN1KMT2AALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616583-A | GASTROINTESTINAL MOTILITY | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-04-01 | — | — | US | disclosed |