Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371216 | 0.74 | MGLL (0.70) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL7035034 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL735230 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL31452685 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL8863096 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL8862894 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL40386 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL9307539 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL5970073 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 | |
| SCHEMBL7198335 | 0.73 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629264-A | 2-aryl-5,6-dihydropyrimidinones and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0733622-A1 | 2-Aryl-5,6-dihydropyrimidinones and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |