Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.33 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772527 | 0.74 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL30736254 | 0.73 | CYP19A1 (0.40) | CYP19A1ELANEHTTKMT2ACYP1A2 | |
| SCHEMBL1693953 | 0.71 | CDK2 (0.49) | CYP19A1ELANEHTTNCOA3ALDH1A1 | |
| SCHEMBL343454 | 0.69 | IMPDH2 (0.41) | CYP19A1HTTNCOA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5492666 | 0.69 | GAA (0.35) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8829351 | 0.69 | GAA (0.37) | CYP19A1CYP3A4GAA | |
| SCHEMBL21863623 | 0.69 | IDO1 (0.32) | CYP19A1CYP3A4GAA | |
| SCHEMBL8829194 | 0.69 | CYP19A1 (0.38) | CYP19A1CYP3A4GAASLC22A12 | |
| Hydrochloric Acid SCHEMBL29572128 | 0.69 | CDK2 (0.47) | CYP19A1ELANEHTTNCOA3ALDH1A1 | |
| SCHEMBL15158038 | 0.68 | CDK2 (0.42) | CYP19A1ELANEALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844318-B | Be used for the treatment of the compound of respiratory syncytial virus infection | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-04-13 | — | — | CN | claimed |
| CN-102844318-A | Compounds for treating respiratory syncytial virus infections | BIOTA SCIENT MAN | 2012-12-26 | — | — | CN | claimed |
| EP-4547669-A1 | INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2025-05-07 | — | — | EP | disclosed |
| CN-119451964-A | FGFR2 and FGFR3 inhibitors and uses thereof | 英矽智能科技知识产权有限公司 | 2025-02-14 | — | — | CN | disclosed |
| WO-2024002157-A1 | INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-01-04 | — | — | WO | disclosed |
| CN-102844318-B | Be used for the treatment of the compound of respiratory syncytial virus infection | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-04-13 | — | — | CN | disclosed |
| CN-102844318-A | Compounds for treating respiratory syncytial virus infections | BIOTA SCIENT MAN | 2012-12-26 | — | — | CN | disclosed |
| US-5593984-A | Cephalosporin derivatives | YUHAN CORPORATION (KR) | 1997-01-14 | — | — | US | disclosed |
| EP-0662973-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994007898-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1994-04-14 | — | — | WO | disclosed |