Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252963 | 0.86 | IMPDH2 (0.39) | IMPDH2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL6005115 | 0.78 | ALOX15 (0.36) | ALOX15 | |
| SCHEMBL28646583 | 0.74 | ALOX15 (0.36) | ALDH1A1MEN1KMT2AALOX15KDM4E | |
| SCHEMBL9098230 | 0.74 | DRD2 (0.45) | IMPDH2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10123651 | 0.72 | CDC7 (0.33) | IMPDH2ALDH1A1KDM4EGAAGLA | |
| SCHEMBL10123575 | 0.71 | MAOA (0.35) | IMPDH2TSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3670867 | 0.69 | ALDH1A1 (0.37) | TSHRALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL8829307 | 0.69 | CYP19A1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL30736254 | 0.69 | CYP19A1 (0.40) | KMT2ALMNAMAPTGAAHTT | |
| SCHEMBL10123585 | 0.69 | ALDH1A1 (0.35) | IMPDH2TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276343-B | Preparation method of fluorescent probe for detecting trace iron ions in chlorobenzene | 中国石油化工股份有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-113582989-B | Preparation method of cyanized or thiocyanized indolizine and derivatives thereof | 广东药科大学 | 2022-07-08 | — | — | CN | claimed |
| CN-114276343-A | Preparation method of fluorescent probe for detecting trace iron ions in chlorobenzene | 中石化南京化工研究院有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-113582989-A | Preparation method of cyanized or thiocyanized indolizine and derivatives thereof | 广东药科大学 | 2021-11-02 | — | — | CN | claimed |
| CN-106661019-A | Indolizine derivatives as phoshoinositide 3-kinases inhibitors | 奇斯药制品公司 | 2017-05-10 | — | — | CN | claimed |
| US-9469741-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2016-10-18 | — | — | US | claimed |
| EP-2203482-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORP (JP) | 2015-11-25 | — | — | EP | claimed |
| CN-104945540-A | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORP | 2015-09-30 | — | — | CN | claimed |
| US-20150267031-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2015-09-24 | — | — | US | claimed |
| US-9085646-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2015-07-21 | — | — | US | claimed |
| US-20130066016-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-14 | — | — | US | claimed |
| US-8362156-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2013-01-29 | — | — | US | claimed |
| US-8314189-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2012-11-20 | — | — | US | claimed |
| US-20100280217-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-11-04 | — | — | US | claimed |
| CN-101874044-A | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORP | 2010-10-27 | — | — | CN | claimed |
| EP-2203482-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | Bridgestone Corporation (JP) | 2010-07-07 | — | — | EP | claimed |
| WO-2009051702-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-04-23 | — | — | WO | claimed |
| WO-2009051700-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (US) | 2009-04-23 | — | — | WO | claimed |
| US-20090099325-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION | 2009-04-16 | — | — | US | claimed |
| JP-3099079-A | — | — | None | — | — | JP | disclosed |
| WO-2026102105-A1 | FUNCTIONAL POLYBUTADIENE AND CARBON BLACK IN RUBBER COMPOUNDS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2026-05-15 | — | — | WO | disclosed |
| CN-114276343-B | Preparation method of fluorescent probe for detecting trace iron ions in chlorobenzene | 中国石油化工股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-114276343-B | Preparation method of fluorescent probe for detecting trace iron ions in chlorobenzene | 中国石油化工股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| US-11512148-B2 | Composition including multiple terminally functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2022-11-29 | — | — | US | disclosed |
| CN-113582989-B | Preparation method of cyanized or thiocyanized indolizine and derivatives thereof | 广东药科大学 | 2022-07-08 | — | — | CN | disclosed |
| US-20220153885-A1 | PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2022-05-19 | — | — | US | disclosed |
| CN-114276343-A | Preparation method of fluorescent probe for detecting trace iron ions in chlorobenzene | 中石化南京化工研究院有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-113582989-A | Preparation method of cyanized or thiocyanized indolizine and derivatives thereof | 广东药科大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-109415457-B | Method for preparing functionalized polymers | 株式会社普利司通 | 2021-05-25 | — | — | CN | disclosed |
| CN-111269228-B | Preparation method of indolizine ring-1, 2-diketone and derivative thereof with fluorescence activity | 广东药科大学 | 2021-04-23 | — | — | CN | disclosed |
| EP-3458488-B1 | PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2020-12-30 | — | — | EP | disclosed |
| US-20200369791-A1 | Composition Including Multiple Terminally Functionalized Polymers | BRIDGESTONE CORPORATION (JP) | 2020-11-26 | — | — | US | disclosed |
| US-20200190293-A1 | RUBBER COMPOSITION, METHOD FOR MANUFACTURING RUBBER COMPOSITION, AND TIRE | BRIDGESTONE CORPORATION (JP) | 2020-06-18 | — | — | US | disclosed |
| CN-111269228-A | Preparation method of indolizine ring-1, 2-diketone and derivative thereof with fluorescence activity | 广东药科大学 | 2020-06-12 | — | — | CN | disclosed |
| EP-3608363-A1 | RUBBER COMPOSITION, METHOD FOR PRODUCING RUBBER COMPOSITION, AND TIRE | Bridgestone Corporation (JP) | 2020-02-12 | — | — | EP | disclosed |
| US-10550203-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2020-02-04 | — | — | US | disclosed |
| CN-110494480-A | Rubber composition, the manufacturing method of rubber composition and tire | BRIDGESTONE CORP | 2019-11-22 | — | — | CN | disclosed |
| US-10370460-B1 | Process for producing functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2019-08-06 | — | — | US | disclosed |
| US-20190185598-A1 | Process For Producing Functionalized Polymers | BRIDGESTONE CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
| EP-3458488-A1 | PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS | Bridgestone Corporation (JP) | 2019-03-27 | — | — | EP | disclosed |
| CN-109415457-A | The method for preparing functionalized polymeric | 株式会社普利司通 | 2019-03-01 | — | — | CN | disclosed |
| US-20180319905-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-11-08 | — | — | US | disclosed |
| US-9884928-B2 | Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group | BRIDGESTONE CORPORATION (JP) | 2018-02-06 | — | — | US | disclosed |
| WO-2017201397-A1 | PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2017-11-23 | — | — | WO | disclosed |
| US-9738738-B2 | Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group | BRIDGESTONE CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| EP-3029074-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORP (JP) | 2017-08-02 | — | — | EP | disclosed |
| CN-106661019-A | Indolizine derivatives as phoshoinositide 3-kinases inhibitors | 奇斯药制品公司 | 2017-05-10 | — | — | CN | disclosed |
| US-9643969-B2 | (aza)indolizine derivative and pharmaceutical use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2017-05-09 | — | — | US | disclosed |
| US-20170015760-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2017-01-19 | — | — | US | disclosed |
| US-9487476-B2 | Catechol diethers as potent anti-HIV agents | YALE UNIVERSITY (US) | 2016-11-08 | — | — | US | disclosed |
| US-9469741-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20160289355-A1 | POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP | BRIDGESTONE CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| US-20160289354-A1 | POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP | BRIDGESTONE CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3029074-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | Bridgestone Corporation (JP) | 2016-06-08 | — | — | EP | disclosed |
| EP-2203482-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORP (JP) | 2015-11-25 | — | — | EP | disclosed |
| CN-104945540-A | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORP | 2015-09-30 | — | — | CN | disclosed |
| US-20150267031-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2015-09-24 | — | — | US | disclosed |
| US-9085646-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2015-07-21 | — | — | US | disclosed |
| CN-102365281-B | Indolizine derivative and medical application thereof | KISSEI PHARMACEUTICAL | 2014-11-12 | — | — | CN | disclosed |
| US-20140288017-A1 | CATECHOL DIETHERS AS POTENT ANTI-HIV AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-09-25 | — | — | US | disclosed |
| US-8748452-B2 | Indolizine derivative and use thereof for medical purposes | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2014-06-10 | — | — | US | disclosed |
| US-8748452-B2 | Indolizine derivative and use thereof for medical purposes | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2014-06-10 | — | — | US | disclosed |
| US-8748452-B2 | Indolizine derivative and use thereof for medical purposes | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20130217878-A1 | (AZA)INDOLIZINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| EP-2415771-B1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL (JP) | 2013-07-31 | — | — | EP | disclosed |
| WO-2013056003-A2 | CATECHOL DIETHERS AS POTENT ANTI-HIV AGENTS | YALE UNIVERSITY (US) | 2013-04-18 | — | — | WO | disclosed |
| US-20130066016-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-14 | — | — | US | disclosed |
| US-8362156-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2013-01-29 | — | — | US | disclosed |
| US-8314189-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2012-11-20 | — | — | US | disclosed |
| US-8309657-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2012-11-13 | — | — | US | disclosed |
| EP-1990343-B1 | Azaindoles | AVENTIS PHARMA LTD (GB) | 2012-04-04 | — | — | EP | disclosed |
| EP-2415771-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| EP-2415771-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120015972-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20120015972-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20120015972-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-01-19 | — | — | US | disclosed |
| CN-102239211-A | Rubber composition | BRIDGESTONE CORP | 2011-11-09 | — | — | CN | disclosed |
| US-20110196086-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-08-11 | — | — | US | disclosed |
| EP-2336233-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-7943616-B2 | Protein kinase inhibitors; astham; psoriasis; antiinflammatory agents; inflammatory bowel disorders | AVENTIS PHARMACEUTICALS INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100280217-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-11-04 | — | — | US | disclosed |
| CN-101874044-A | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORP | 2010-10-27 | — | — | CN | disclosed |
| EP-2233486-A1 | Azaindoles | Aventis Pharma Limited (GB) | 2010-09-29 | — | — | EP | disclosed |
| EP-1263759-B1 | AZAINDOLES | AVENTIS PHARMA LTD (GB) | 2010-09-08 | — | — | EP | disclosed |
| EP-2203482-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | Bridgestone Corporation (JP) | 2010-07-07 | — | — | EP | disclosed |
| US-20100168125-A1 | INDOLIZINES AND AZA-ANALOG DERIVATIVES THEREOF AS CNS ACTIVE COMPOUNDS | DONSBACH, MARTIN (DE) | 2010-07-01 | — | — | US | disclosed |
| CN-100509811-C | Azaindoles | AVENTIS PHARMA LTD (GB) | 2009-07-08 | — | — | CN | disclosed |
| WO-2009051702-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009051700-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |
| US-20090099325-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION | 2009-04-16 | — | — | US | disclosed |
| EP-1990343-A2 | Azaindoles | Aventis Pharma Limited (GB) | 2008-11-12 | — | — | EP | disclosed |
| CN-100379734-C | Azaindoles | AVENTIS PHARMA LTD (GB) | 2008-04-09 | — | — | CN | disclosed |
| US-7227020-B2 | Azaindoles | AVENTIS PHARMA LIMITED (GB) | 2007-06-05 | — | — | US | disclosed |
| US-20050267304-A1 | Protein kinase inhibitors; astham; psoriasis; antiinflammatory agents; inflammatory bowel disorders | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-01 | — | — | US | disclosed |
| CN-1665809-A | Azaindoles | AVENTIS PHARMA LTD (GB) | 2005-09-07 | — | — | CN | disclosed |
| US-6897207-B2 | Azaindoles | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-24 | — | — | US | disclosed |
| CN-1615873-A | Azaindoles compound | AVENTIS PHARMA LTD (GB) | 2005-05-18 | — | — | CN | disclosed |
| US-20040198737-A1 | Azaindoles | AVENTIS PHARMA LIMITED (GB) | 2004-10-07 | — | — | US | disclosed |
| US-6770643-B2 | Azaindoles | AVENTIS PHARMA LIMITED (GB) | 2004-08-03 | — | — | US | disclosed |
| US-20040053931-A1 | Azaindoles | AVENTIS PHARMACEUTICALS INC. | 2004-03-18 | — | — | US | disclosed |
| EP-1397360-A1 | AZAINDOLES | Aventis Pharma Limited (GB) | 2004-03-17 | — | — | EP | disclosed |
| US-20040009983-A1 | Azaindoles | AVENTIS PHARMA LIMITED (GB) | 2004-01-15 | — | — | US | disclosed |
| CN-1413213-A | Azaindoles | AVENTIS PHARMA LTD (GB) | 2003-04-23 | — | — | CN | disclosed |
| WO-2003000688-A1 | AZAINDOLES | AVENTIS PHARMA LIMITED (GB) | 2003-01-03 | — | — | WO | disclosed |
| EP-1263759-A2 | AZAINDOLES | Aventis Pharma Limited (GB) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001047922-A2 | AZAINDOLES | AVENTIS PHARMA LIMITED (GB) | 2001-07-05 | — | — | WO | disclosed |
| CN-1059723-A | Hete rocyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-03-25 | — | — | CN | disclosed |
| JP-H0399079-A | INDOLIZINE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1991-04-24 | — | — | JP | disclosed |
| JP-H0399079-A | INDOLIZINE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1991-04-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198737-A1 | Azaindoles | CCNY, CCNO, CNKSR1 | IMPDH2 4148/4885TSHR 608/4885ALDH1A1 4397/4885 |
| US-20100168125-A1 | INDOLIZINES AND AZA-ANALOG DERIVATIVES THEREOF AS CNS ACTIVE COMPOUNDS | INMT, AANAT, AZI2 | IMPDH2 106/4885TSHR 909/4885ALDH1A1 720/4885 |
| US-20140288017-A1 | CATECHOL DIETHERS AS POTENT ANTI-HIV AGENTS | COMT, NNMT, PNMT | IMPDH2 624/4885TSHR 4865/4885ALDH1A1 572/4885 |
| US-20040053931-A1 | Azaindoles | CDKN1A, CDK7, CDK2 | IMPDH2 394/4885TSHR 3097/4885ALDH1A1 939/4885 |
| US-20130217878-A1 | (AZA)INDOLIZINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | XDH, CHRM1, PON1 | IMPDH2 31/4885TSHR 1426/4885ALDH1A1 331/4885 |
| US-20120015972-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | XDH, INMT, PON1 | IMPDH2 13/4885TSHR 1474/4885ALDH1A1 397/4885 |
| US-20040009983-A1 | Azaindoles | CCNY, CCNO, CKS2 | IMPDH2 4243/4885TSHR 252/4885ALDH1A1 4673/4885 |
| US-20050267304-A1 | Protein kinase inhibitors; astham; psoriasis; antiinflammatory agents; inflammatory bowel disorders | MAP3K20, MAP3K12, MAP3K19 | IMPDH2 1472/4885TSHR 4578/4885ALDH1A1 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.