SCHEMBL8829702

SCHEMBL8829702

CCc1cn(-c2ccc(F)c(C(F)(F)F)c2)c(=N)s1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 12/20 0.40
RXRA P19793 7/20 0.39
GRIN1 Q05586 7/20 0.39
GRIN2B Q13224 7/20 0.39
F2RL3 Q96RI0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8425364 0.82 AR (0.42) ARRXRAGRIN1GRIN2B
Hydrochloric Acid SCHEMBL9250208 0.81 AR (0.41) ARRXRAGRIN1GRIN2B
SCHEMBL8010810 0.77 HTT (0.41) RXRAGRIN1GRIN2B
SCHEMBL9226972 0.74 TDP1 (0.36)
SCHEMBL7254837 0.68 AR (0.41) ARRXRAGRIN1GRIN2B
SCHEMBL9494769 0.64 AR (0.43) ARRXRAGRIN1GRIN2B
SCHEMBL5023454 0.63 AR (0.48) ARRXRAGRIN1GRIN2B
SCHEMBL10299806 0.63 AR (0.48) ARRXRAGRIN1GRIN2B
SCHEMBL9255699 0.63 AR (0.39) ARRXRAGRIN1GRIN2B
SCHEMBL8425365 0.61 AR (0.46) ARRXRAGRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5463069-A Process of producing 2-iminothiazoline derivatives and process of producing their intermediates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-10-31 US claimed
CN-1125045-C Process for producing intermecliates used in process for producing-2-iminothiazoline derivatives SUMITOMO CHEMICAL CO (JP) 2003-10-22 CN disclosed
CN-1073099-C Process for producing intermecliates used in process for producing 2-iminothiazoline derivatives SUMITOMO CHEMICAL CO (JP) 2001-10-17 CN disclosed
CN-1228420-A Process for producing intermecliates used in process for producing-2-iminothiazoline derivatives SUMITOMO CHEMICAL CO (JP) 1999-09-15 CN disclosed
CN-1225363-A Process for producing intermediate in process for producing 2-iminothiazoline derivative SUMITOMO CHEMICAL CO (JP) 1999-08-11 CN disclosed
CN-1042224-C Process for preparing 2-iminothiazoline derivatives SUMITOMO CHEMICAL CO (JP) 1999-02-24 CN disclosed
US-5684196-A N-SUBSTITUTED-N-ARYLCYANAMIDE SUMITOMO CHEMICAL CO., LTD. (JP) 1997-11-04 US disclosed
US-5648533-A Process of producing 2-iminothiazoline derivatives and process of producing their intermediates SUMITOMO CHEMICAL CO., LTD. (JP) 1997-07-15 US disclosed
EP-0600489-B1 Process for producing 2-iminothiazoline derivatives and process for producing their intermediates SUMITOMO CHEMICAL CO (JP) 1996-11-06 EP disclosed
US-5463069-A Process of producing 2-iminothiazoline derivatives and process of producing their intermediates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-10-31 US disclosed
CN-1097007-A Process for preparing 2-iminothiazoline derivatives and process for preparing intermediates thereof SUMITOMO CHEMICAL CO (JP) 1995-01-04 CN disclosed
EP-0600489-A1 Process for producing 2-iminothiazoline derivatives and process for producing their intermediates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-06-08 EP disclosed