Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829702 | 0.74 | AR (0.40) | — | |
| SCHEMBL8010810 | 0.72 | HTT (0.41) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL25002872 | 0.68 | TDP1 (0.41) | TDP1L3MBTL1POLBHCAR1ALDH1A1 | |
| SCHEMBL19732301 | 0.62 | TRPV1 (0.61) | ALDH1A1TRPV1APPAMY1A | |
| SCHEMBL25644300 | 0.62 | KDM4E (0.49) | TDP1L3MBTL1POLBHCAR1ALDH1A1 | |
| SCHEMBL13282055 | 0.62 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AHSD11B1 | |
| SCHEMBL12871677 | 0.61 | LMNA (0.40) | TDP1L3MBTL1HCAR1ALDH1A1MAPT | |
| SCHEMBL3303708 | 0.61 | ALDH1A1 (0.53) | TDP1L3MBTL1POLBHCAR1ALDH1A1 | |
| SCHEMBL28165028 | 0.60 | IDO1 (0.42) | TDP1L3MBTL1POLBALDH1A1MEN1 | |
| SCHEMBL239404 | 0.59 | IDO1 (0.55) | TDP1POLBALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446802-B1 | Iminothiazolines, their production and use as herbicides, and intermediates for their production | SUMITOMO CHEMICAL CO (JP) | 1995-06-07 | — | — | EP | disclosed |
| EP-0446802-A1 | Iminothiazolines, their production and use as herbicides, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |