SCHEMBL8829804

SCHEMBL8829804

CCCCc1cc(C(=O)O)cc(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cn1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 6/20 0.44
AGTR2 P50052 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9223003 0.91 AGTR1 (0.39) AGTR1
SCHEMBL8887101 0.89 AGTR1 (0.51) AGTR1AGTR2
SCHEMBL8829807 0.88 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL8010421 0.86 AGTR1 (0.40) AGTR1AGTR2
SCHEMBL8437583 0.86 AGTR1 (0.40) AGTR1
SCHEMBL5814612 0.85 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL8829800 0.85 AGTR1 (0.36) AGTR1
SCHEMBL8436392 0.85 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL9227513 0.84 AGTR1 (0.50) AGTR1AGTR2
SCHEMBL7998092 0.84 AGTR1 (0.44) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624583-B1 Substituted pyridylmethylpyridone as angiotensine II antagonists BAYER AG (DE) 1997-07-23 EP disclosed
US-5407948-A For treating hypertension, atherosclerosis BAYER AKTIENGESELLSCHAFT (DE) 1995-04-18 US disclosed
EP-0624583-A1 Substituted mono- and bipyridylmethylpyridone as angiotensine II antagonists BAYER AG (DE) 1994-11-17 EP disclosed