Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894371 | 0.91 | — | — | |
| SCHEMBL8883738 | 0.91 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8886997 | 0.90 | — | — | |
| SCHEMBL8886994 | 0.90 | — | — | |
| SCHEMBL9533318 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2 | |
| Potassium SCHEMBL8886365 | 0.90 | — | — | |
| SCHEMBL7997883 | 0.90 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL8829804 | 0.89 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8435622 | 0.88 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9568738 | 0.88 | PPARG (0.44) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542059-A1 | Substituted biphenylpyridinones as angiotensin II antagonists | BAYER AG (DE) | 1993-05-19 | — | — | EP | claimed |
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | claimed |
| US-5599823-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| US-5356911-A | Hypotensive agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| EP-0572455-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | Astra Pharmaceuticals Limited (GB) | 1993-12-08 | — | — | EP | disclosed |
| EP-0542059-A1 | Substituted biphenylpyridinones as angiotensin II antagonists | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992014714-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | FISONS PLC (GB) | 1992-09-03 | — | — | WO | disclosed |
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | disclosed |