SCHEMBL8829915

SCHEMBL8829915

CC(Cc1c[nH]c2ccccc12)(NC(=O)O)C(=O)NCCN1CCCC1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 6/20 0.56
NMBR P28336 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8829853 0.99 CCKBR (0.55) CCKBRNMBR
SCHEMBL8829913 0.92 CCKBR (0.54) CCKBRNMBR
SCHEMBL8829868 0.92 CCKBR (0.54) CCKBRNMBR
SCHEMBL8829876 0.84 CCKBR (0.68) CCKBRNMBR
SCHEMBL6892425 0.83 CCKBR (0.78) CCKBRNMBR
SCHEMBL8829903 0.82 NMBR (0.60) CCKBRNMBR
SCHEMBL8829899 0.82 NMBR (0.60) CCKBRNMBR
SCHEMBL8829907 0.82 CCKBR (0.60) CCKBRNMBR
SCHEMBL9377089 0.80 NMBR (0.61) CCKBRNMBR
SCHEMBL10625743 0.80 CCKBR (0.68) CCKBRNMBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631281-A COMPOUNDS FOR TREATMENT OF ANXIETY WITH INDOLE AMIDES WARNER-LAMBERT COMPANY (US) 1997-05-20 US disclosed
US-5622983-A ANTIOBESITY AGENTS, ANTIPSYCHOTIC AGENTS, ANTIULCER AGENTS WARNER-LAMBERT COMPANY (US) 1997-04-22 US disclosed
US-5278316-A Indoles WARNER-LAMBERT COMPANY (US) 1994-01-11 US disclosed