Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31043442 | 0.86 | ENPP2 (0.34) | ENPP2ORAI1ORAI2ORAI3TSPO | |
| SCHEMBL29398133 | 0.85 | ENPP2 (0.33) | MAPTGAAALDH1A1TP53TSHR | |
| SCHEMBL8830001 | 0.83 | MAPT (0.39) | MAPTGAAALDH1A1TP53TSHR | |
| SCHEMBL6340984 | 0.79 | TDP1 (0.38) | MAPTGAAALDH1A1TSHRENPP2 | |
| SCHEMBL29023721 | 0.77 | GAA (0.48) | MAPTGAAALDH1A1TP53TSHR | |
| SCHEMBL6678412 | 0.77 | ENPP2 (0.44) | MAPTGAAALDH1A1TP53TSHR | |
| SCHEMBL29706601 | 0.77 | ENPP2 (0.44) | MAPTGAAALDH1A1TP53TSHR | |
| SCHEMBL19834040 | 0.76 | ORAI1 (0.41) | MAPTGAAALDH1A1TP53TSHR | |
| SCHEMBL2458146 | 0.75 | TSPO (0.46) | MAPTGAAALDH1A1TP53TSHR | |
| SCHEMBL2539698 | 0.73 | CA1 (0.57) | MAPTGAAALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101983384-A | Prolyl hydroxylase inhibitors | SMITHKLINE BEECHAM CORP | 2011-03-02 | — | — | CN | disclosed |
| US-5607803-A | Decolorizable toner and a decolorizable toner production process | SHOWA DENKO K.K. (JP) | 1997-03-04 | — | — | US | disclosed |