Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270852 | 0.79 | KDM4E (0.37) | NOS3NOS1NOS2UHRF1KDM4E | |
| SCHEMBL29770726 | 0.73 | NOS3 (0.55) | NOS3NOS1NOS2BCHEACHE | |
| SCHEMBL4928360 | 0.73 | NOS3 (0.55) | NOS3NOS1NOS2BCHEACHE | |
| SCHEMBL24858515 | 0.73 | KDM4E (0.31) | NOS3NOS1NOS2KDM4ECYP3A4 | |
| SCHEMBL4926313 | 0.69 | NOS3 (0.60) | NOS3NOS1NOS2BCHEACHE | |
| SCHEMBL10287003 | 0.66 | KDM4E (0.33) | UHRF1KDM4E | |
| SCHEMBL19999035 | 0.64 | ACHE (0.47) | NOS3NOS1NOS2UHRF1ACHE | |
| SCHEMBL10287322 | 0.62 | UGT2B17 (0.47) | NOS3NOS1NOS2UHRF1ACHE | |
| SCHEMBL14884979 | 0.62 | UGT2B17 (0.47) | NOS3NOS1NOS2UHRF1ACHE | |
| SCHEMBL10287314 | 0.62 | UGT2B17 (0.47) | NOS3NOS1NOS2UHRF1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038521-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-03-29 | — | — | WO | disclosed |