Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.59 |
| ▸ | HTR7 | P34969 | 8/20 | 0.59 |
| ▸ | HTR6 | P50406 | 7/20 | 0.59 |
| ▸ | DRD2 | P14416 | 6/20 | 0.59 |
| ▸ | HTR1A | P08908 | 4/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831337 | 0.98 | HTR2A (0.60) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL8831356 | 0.92 | HTR2A (0.60) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL8831311 | 0.88 | HTR2A (0.70) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL8831391 | 0.85 | HTR7 (0.62) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL8831833 | 0.85 | HTR2A (0.67) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL8831867 | 0.83 | HTR2A (0.60) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL8831368 | 0.81 | HTR2A (0.60) | HTR2AHTR7HTR6DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9604507 | 0.80 | HTR1A (0.79) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL8831371 | 0.80 | HTR2A (0.68) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL6185115 | 0.79 | HTR2A (0.65) | HTR2AHTR7HTR6DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635506-A1 | COMPOUND WITH ANTIPSYCHOTIC EFFECT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-01-25 | — | — | EP | claimed |
| CN-1050604-C | Compound with antipsychotic effect | MEIJI SEIKA KABUSHIKA KAISHA (JP) | 2000-03-22 | — | — | CN | disclosed |
| US-5599815-A | SIDE EFFECT REDUCTION | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0635506-A1 | COMPOUND WITH ANTIPSYCHOTIC EFFECT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-01-25 | — | — | EP | disclosed |