Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.56 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832170 | 0.92 | BCL9 (0.65) | BCL9CTNNB1MGLLPTPN7PTPN12 | |
| SCHEMBL27517821 | 0.88 | MAPT (0.59) | BCL9CTNNB1MGLLKMT2AMAPT | |
| SCHEMBL11605368 | 0.87 | PTPN7 (0.69) | BCL9CTNNB1PTPN7PTPN12PTPN22 | |
| SCHEMBL7975117 | 0.86 | MGLL (0.62) | BCL9CTNNB1MGLLKMT2AMAPT | |
| SCHEMBL1240044 | 0.86 | MAPT (0.63) | MGLLKMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL1963497 | 0.84 | MAPT (0.62) | MGLLKMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL9308071 | 0.84 | MAPT (0.62) | MGLLKMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL9232088 | 0.84 | MAPT (0.62) | MGLLKMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL51004 | 0.84 | MAPT (0.62) | MGLLKMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL8410318 | 0.84 | MAPT (0.62) | MGLLKMT2AMAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670492-A | BACTERICIDE, ANTITUMOR AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0702014-A1 | DC-89 DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |