Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26992591 | 0.86 | NPC1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL31721248 | 0.75 | CYP1A2 (0.53) | NPC1RAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL15878812 | 0.75 | ALDH1A1 (0.55) | NPC1RAB9AMAPTTSHRMEN1 | |
| SCHEMBL30577603 | 0.75 | MAPT (0.52) | NPC1RAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL21818776 | 0.74 | ALDH1A1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30577688 | 0.74 | MAPT (0.51) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8832211 | 0.74 | CA12 (0.42) | MAPTTSHRKMT2AALDH1A1CYP1A2 | |
| SCHEMBL8573566 | 0.73 | RAB9A (0.50) | NPC1RAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL8832744 | 0.73 | ADORA2A (0.55) | NPC1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8832481 | 0.72 | ALDH1A1 (0.54) | NPC1RAB9AMAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703916-A1 | 14-SUBSTITUTED MARCFORTINES AND DERIVATIVES USEFUL AS ANTIPARASITIC AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1996-04-03 | — | — | EP | claimed |
| WO-1994029319-A1 | 14-SUBSTITUTED MARCFORTINES AND DERIVATIVES USEFUL AS ANTIPARASITIC AGENTS | THE UPJOHN COMPANY (US) | 1994-12-22 | — | — | WO | claimed |
| US-5622913-A | CONTROLLING PLANT GROWTH | AMERICAN CYANAMID COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5599772-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5599773-A | (2-imidazolin-2-yl) fused heteropyridine compounds and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5571773-A | PREEMERGENCE HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| US-5565412-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5565411-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5563113-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5554579-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1996-09-10 | — | — | US | disclosed |
| US-5536702-A | (2-imidazolin-2-yl) fused heteropyridine compounds and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1996-07-16 | — | — | US | disclosed |
| US-5536839-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1996-07-16 | — | — | US | disclosed |
| US-5534483-A | (2-imidazolin-2-yl) fused heteropyridine compounds intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5534485-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5534484-A | (2-imidazolin-2-yl)fused heteropyridine compounds intermediates for the preparation of and use of said compounds and herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5532207-A | CONTROL OF MONO- AND DI-COTYLEDONOUS ANNUAL, PERENNIAL AND AQUATIC PLANTS; PRE- AND POST-EMERGENCE USE | AMERICAN CYANAMID COMPANY (US) | 1996-07-02 | — | — | US | disclosed |
| US-5510319-A | PYRROLO-2,3-B-PYRIDINYL DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-5252538-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0227932-B1 | NOVEL FUSED PYRIDINE COMPOUNDS, INTERMEDIATES FOR THE PREPARATION OF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0227932-A1 | Novel fused pyridine compounds, intermediates for the preparation of, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-07-08 | — | — | EP | disclosed |