Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | CBR1 | P16152 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030457 | 0.87 | TTR (0.53) | LMNAMAPTHPGDNR1I2TTR | |
| SCHEMBL2989844 | 0.80 | S1PR4 (0.42) | LMNAMAPTHPGDNR1I2TTR | |
| SCHEMBL16815380 | 0.79 | TSHR (0.43) | LMNAMAPTHPGDMAPK1S1PR4 | |
| SCHEMBL8096761 | 0.79 | S1PR4 (0.43) | LMNAMAPTHPGDNR1I2TTR | |
| SCHEMBL5604866 | 0.78 | MAPK1 (0.50) | LMNAMAPTHPGDNR1I2TTR | |
| SCHEMBL8832605 | 0.75 | LMNA (0.38) | LMNAMAPTHPGDNR1I2ADORA3 | |
| SCHEMBL196490 | 0.75 | TTR (0.62) | LMNAMAPTHPGDNR1I2TTR | |
| SCHEMBL29687129 | 0.75 | TTR (0.62) | LMNAMAPTHPGDNR1I2TTR | |
| SCHEMBL7186092 | 0.74 | TTR (0.75) | LMNAMAPTHPGDNR1I2TTR | |
| SCHEMBL829749 | 0.74 | TTR (0.56) | LMNAMAPTHPGDNR1I2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215106-A1 | POLYORGANOSILSESQUIOXANE, MULTILAYER BODY AND SURFACE-COATED MOLDED BODY | 株式会社ダイセル (JP) | 2021-10-28 | — | — | WO | disclosed |
| US-5622784-A | WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM | SEIKO EPSON CORPORATION (JP) | 1997-04-22 | — | — | US | disclosed |