SCHEMBL8833152

SCHEMBL8833152

C[Si](C)(C)OCc1ccco1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
GAA P10253 1/20 0.47
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
MAPK1 P28482 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 3/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 3/20 0.38
HTT P42858 2/20 0.38
TP53 P04637 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CHRM2 P08172 1/20 0.37
POLB P06746 3/20 0.37
TSHR P16473 2/20 0.36
MGMT P16455 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11418453 0.87 ALDH1A1 (0.53) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL287571 0.87 ALDH1A1 (0.53) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL288183 0.84 ALDH1A1 (0.50) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL11418456 0.82 ALDH1A1 (0.49) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL13452758 0.82 ALDH1A1 (0.49) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL11431883 0.82 ALDH1A1 (0.49) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL11618786 0.81 ALDH1A1 (0.52) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL1262629 0.80 ALDH1A1 (0.47) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL8100617 0.79 ALDH1A1 (0.46) ALDH1A1GAASLC1A3SLC1A2SLC1A1
SCHEMBL18417876 0.79 ALDH1A1 (0.46) ALDH1A1GAASLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021215106-A1 POLYORGANOSILSESQUIOXANE, MULTILAYER BODY AND SURFACE-COATED MOLDED BODY 株式会社ダイセル (JP) 2021-10-28 WO disclosed
US-5622784-A WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM SEIKO EPSON CORPORATION (JP) 1997-04-22 US disclosed