Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833852 | 0.93 | HDAC2 (0.54) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| Hydrochloric Acid SCHEMBL10623276 | 0.84 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL570578 | 0.81 | — | — | |
| SCHEMBL3628743 | 0.80 | HDAC2 (0.53) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL518453 | 0.79 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL1628262 | 0.79 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL6912982 | 0.79 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| Hydrochloric Acid SCHEMBL8599803 | 0.79 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL11169395 | 0.79 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL20184157 | 0.79 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-4369206-A | HARDENING COATING WITH AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-18 | — | — | US | disclosed |
| EP-0008626-B1 | AMMONIUM SALTS OF ALPHA-KETOCARBOXYLIC ACIDS, THEIR USE IN THE PREPARATION OF AMINES AND COATING MATERIALS CONTAINING THEM | BAYER AG (DE) | 1981-07-29 | — | — | EP | disclosed |
| EP-0008626-A1 | Ammonium salts of alpha-ketocarboxylic acids, their use in the preparation of amines and coating materials containing them | BAYER AG (DE) | 1980-03-19 | — | — | EP | disclosed |