Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 known ✓ | Q92769 | 4/20 | 0.57 |
| ▸ | HDAC4 known ✓ | P56524 | 2/20 | 0.57 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC1 known ✓ | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC3 known ✓ | O15379 | 2/20 | 0.48 |
| ▸ | HDAC7 known ✓ | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC5 known ✓ | Q9UQL6 | 1/20 | 0.48 |
| ▸ | SLC6A1 known ✓ | P30531 | 1/20 | 0.43 |
| ▸ | GABRP known ✓ | O00591 | 1/20 | 0.43 |
| ▸ | GABRD known ✓ | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 known ✓ | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 known ✓ | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570578 | 0.98 | — | — | |
| SCHEMBL6915117 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL19359633 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL6913508 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL20184157 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL518453 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL6912982 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL11169395 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL1628262 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL6915122 | 0.95 | HDAC2 (0.57) | HDAC2HDAC4HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629634-B1 | Process for the preparation of taurocholic acids | SANOFI SA (FR) | 1998-02-25 | — | — | EP | claimed |
| US-5565587-A | TREATING CHOLANIC ACID WITH ACID CHLORIDE IN PRESENCE OF TERTIARY AMINE, TREATING RESULTING MIXED ANHYDRIDE WITH TAURINE | SANOFI (FR) | 1996-10-15 | — | — | US | claimed |
| CN-114423744-A | Method for producing epoxy compound | 株式会社大赛璐 | 2022-04-29 | — | — | CN | disclosed |
| WO-2021054224-A1 | EPOXY COMPOUND PRODUCTION METHOD | 株式会社ダイセル | 2021-03-25 | — | — | WO | disclosed |
| US-5707557-A | Photochromic 3H-naphthopyrans | OPTISCHE WERKE G. RODENSTOCK (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5565587-A | TREATING CHOLANIC ACID WITH ACID CHLORIDE IN PRESENCE OF TERTIARY AMINE, TREATING RESULTING MIXED ANHYDRIDE WITH TAURINE | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5508453-A | Intermediate for use in the preparation of taurocholanic acids | SANOFI (FR) | 1996-04-16 | — | — | US | disclosed |
| US-5061667-A | REDUCED POWDERING OF POLYMER DURING POLYMERIZATION | TOG NENRYO KOGYO KK (TONEN CORPORATION) (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0173470-B1 | CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS | Tonen Corporation (JP) | 1991-03-20 | — | — | EP | disclosed |
| EP-0173472-B1 | CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS | Tonen Corporation (JP) | 1990-12-19 | — | — | EP | disclosed |
| EP-0264169-B1 | PROCESS FOR PRODUCING ETHYLENE-PROPYLENE COPOLYMER RUBBER | Tonen Corporation (JP) | 1990-11-22 | — | — | EP | disclosed |
| EP-0136112-A2 | Catalyst component for polymerization of olefins | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1985-04-03 | — | — | EP | disclosed |
| EP-0136113-A2 | Catalyst component for polymerization of olefins | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1985-04-03 | — | — | EP | disclosed |
| EP-0044635-A1 | Catalyst components for polymerization of alpha-olefins and a method for using them | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1982-01-27 | — | — | EP | disclosed |
| US-4299764-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-10 | — | — | US | disclosed |
| US-4129704-A | Polymerization of vinyl monomers employing a diperoxyester mixture composition prepared by reacting dihydroperoxide and peroxyester forming carbonyl compounds | PENNWALT CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4097408-A | FROM DIHYDOPEROXIDE AND CARBONYL COMPOUND, POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4001218-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3982011-A | ANTIBIOTICS, ANIMAL GROWTH PROMOTERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | disclosed |
| US-3931153-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |