Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431017 | 0.91 | CTSS (0.41) | CTSSADRB3ADRA2BADRA2C | |
| SCHEMBL10273195 | 0.85 | CTSS (0.33) | CTSSPDE4B | |
| SCHEMBL313037 | 0.76 | UCHL1 (0.39) | CTSSADRB3ADRA2BADRA2CPDE4B | |
| SCHEMBL7936436 | 0.76 | CTSS (0.44) | CTSSADRB3ADRA2BADRA2CPDE4B | |
| SCHEMBL1101734 | 0.76 | CTSS (0.44) | CTSSADRB3ADRA2BADRA2CPDE4B | |
| SCHEMBL3808212 | 0.76 | UCHL1 (0.39) | CTSSADRB3ADRA2BADRA2CPDE4B | |
| SCHEMBL882945 | 0.75 | CTSS (0.40) | CTSSADRB3ADRA2BADRA2C | |
| SCHEMBL3429241 | 0.75 | CTSS (0.40) | CTSSADRB3ADRA2BADRA2C | |
| SCHEMBL3479466 | 0.74 | CTSS (0.40) | CTSS | |
| SCHEMBL3429578 | 0.73 | CTSS (0.39) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |