Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27752130 | 0.83 | MAPT (0.43) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL9522375 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2SRD5A2HPGD | |
| SCHEMBL9522384 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2SRD5A2HPGD | |
| SCHEMBL21628043 | 0.82 | TYR (0.46) | TSHRTP53TYR | |
| SCHEMBL24654394 | 0.82 | KDM4E (0.46) | TSHRALDH1A1KMT2ASMN1; SMN2TYR | |
| SCHEMBL9636818 | 0.82 | TSHR (0.48) | TSHRTP53ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2009011 | 0.80 | TP53 (0.46) | TSHRTP53ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL26935634 | 0.79 | HSD17B1 (0.52) | KMT2ASMN1; SMN2HPGDMAPTRXRA | |
| SCHEMBL8833980 | 0.79 | ALDH1A1 (0.56) | TSHRALDH1A1KMT2AMAPTCA1 | |
| SCHEMBL6832411 | 0.78 | TSHR (0.55) | TSHRTP53ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629200-A | MICROORGANISM | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-13 | — | — | US | disclosed |