Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833334 | 0.87 | POLB (0.44) | RAB9AALDH1A1SMN1; SMN2NPC1TSHR | |
| SCHEMBL8834630 | 0.81 | CCNE1 (0.40) | CCNE1CDK2CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL8832986 | 0.80 | CCNE1 (0.44) | CCNE1CDK2CDK5RAB9AALDH1A1 | |
| SCHEMBL8834023 | 0.79 | CCNE1 (0.38) | CCNE1CDK2CDK5ALDH1A1L3MBTL1 | |
| SCHEMBL8833079 | 0.78 | FDPS (0.40) | CCNE1CDK2CDK5RAB9AALDH1A1 | |
| SCHEMBL8834051 | 0.77 | CCNE1 (0.47) | CCNE1CDK2CDK5RAB9AALDH1A1 | |
| SCHEMBL8833431 | 0.76 | CCNE1 (0.41) | CCNE1CDK2CDK5RAB9ASMN1; SMN2 | |
| SCHEMBL26759082 | 0.75 | CDK2 (0.50) | CCNE1CDK2CDK5RAB9AALDH1A1 | |
| SCHEMBL8834125 | 0.74 | FDPS (0.37) | CCNE1CDK2CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL8833680 | 0.73 | SMN1; SMN2 (0.43) | CCNE1CDK2CDK5ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |