Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833640 | 0.87 | CCNE1 (0.46) | NPC1SMN1; SMN2KMT2ARAB9AALDH1A1 | |
| SCHEMBL8834453 | 0.78 | SMN1; SMN2 (0.43) | POLBLMNANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8834630 | 0.75 | CCNE1 (0.40) | POLBLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8833431 | 0.73 | CCNE1 (0.41) | LMNANPC1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL8834125 | 0.71 | FDPS (0.37) | SMN1; SMN2KMT2AALDH1A1HTT | |
| SCHEMBL4186314 | 0.69 | GAA (0.59) | LMNAKMT2AALDH1A1GAAAPP | |
| SCHEMBL27764010 | 0.69 | ALDH1A1 (0.59) | LMNAKMT2AALDH1A1GAAAPP | |
| SCHEMBL28527736 | 0.69 | ALDH1A1 (0.50) | LMNANPC1SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL8833591 | 0.69 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2RAB9ATSHR | |
| SCHEMBL2000039 | 0.69 | ALDH1A1 (0.63) | LMNANPC1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |