Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020169 | 0.86 | CHRM1 (0.38) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL9215878 | 0.85 | CHRM1 (0.37) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL8098583 | 0.85 | CHRM1 (0.37) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL9754678 | 0.85 | CHRM1 (0.37) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL8833343 | 0.85 | CHRM1 (0.37) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL9027979 | 0.85 | FAAH (0.33) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL9025504 | 0.85 | FAAH (0.33) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL9221565 | 0.83 | CHRM1 (0.36) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL8833427 | 0.83 | CHRM1 (0.36) | CHRM1LMNAMAPK1RAB9AFAAH | |
| SCHEMBL8832773 | 0.83 | CHRM1 (0.36) | CHRM1LMNAMAPK1RAB9AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608056-A | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021186-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-28 | — | — | WO | disclosed |