Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.30 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027979 | 1.00 | FAAH (0.33) | FAAHCHRM1CYP19A1SIGMAR1LMNA | |
| SCHEMBL8834048 | 0.85 | ECE1 (0.38) | FAAHCHRM1CYP19A1SIGMAR1MGLL | |
| SCHEMBL9027722 | 0.85 | ECE1 (0.38) | FAAHCHRM1CYP19A1SIGMAR1MGLL | |
| SCHEMBL8833653 | 0.85 | CHRM1 (0.35) | FAAHCHRM1CYP19A1SIGMAR1LMNA | |
| SCHEMBL9020169 | 0.82 | CHRM1 (0.38) | FAAHCHRM1CYP19A1SIGMAR1LMNA | |
| SCHEMBL9215878 | 0.81 | CHRM1 (0.37) | FAAHCHRM1CYP19A1SIGMAR1LMNA | |
| SCHEMBL9754678 | 0.81 | CHRM1 (0.37) | FAAHCHRM1CYP19A1SIGMAR1LMNA | |
| SCHEMBL8833343 | 0.81 | CHRM1 (0.37) | FAAHCHRM1CYP19A1SIGMAR1LMNA | |
| SCHEMBL8098583 | 0.81 | CHRM1 (0.37) | FAAHCHRM1CYP19A1SIGMAR1LMNA | |
| SCHEMBL8834131 | 0.81 | CHRM1 (0.35) | FAAHCHRM1SIGMAR1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |