Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834104 | 0.92 | AGTR1 (0.41) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL8833914 | 0.90 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL8833121 | 0.90 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8833882 | 0.89 | RAB9A (0.40) | RAB9AHSD17B10 | |
| SCHEMBL8833340 | 0.88 | AGTR1 (0.38) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL8833764 | 0.83 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL8833864 | 0.81 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL8833300 | 0.77 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8833162 | 0.77 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL8833988 | 0.77 | AGTR1 (0.41) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |