Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834305 | 0.85 | CYSLTR1 (0.69) | CYSLTR1FFAR1AKR1B1CYSLTR2GPBAR1 | |
| SCHEMBL8834954 | 0.82 | CYSLTR1 (0.60) | CYSLTR1FFAR1AKR1B1CYSLTR2ALOX5 | |
| SCHEMBL8890067 | 0.81 | CYSLTR1 (0.63) | CYSLTR1FFAR1AKR1B1CYSLTR2GPBAR1 | |
| SCHEMBL7095887 | 0.80 | CYSLTR1 (0.79) | CYSLTR1FFAR1AKR1B1CYSLTR2GPBAR1 | |
| SCHEMBL10446560 | 0.80 | CYSLTR1 (0.79) | CYSLTR1FFAR1AKR1B1CYSLTR2GPBAR1 | |
| SCHEMBL10446852 | 0.80 | CYSLTR1 (0.75) | CYSLTR1FFAR1AKR1B1CYSLTR2GPBAR1 | |
| SCHEMBL8834670 | 0.79 | CYSLTR1 (0.66) | CYSLTR1FFAR1AKR1B1CYSLTR2GPBAR1 | |
| SCHEMBL8965285 | 0.78 | ALOX5 (0.65) | CYSLTR1FFAR1AKR1B1CYSLTR2ALOX5 | |
| SCHEMBL10544473 | 0.78 | CYSLTR1 (0.84) | CYSLTR1FFAR1AKR1B1CYSLTR2GPBAR1 | |
| SCHEMBL9459982 | 0.78 | FFAR1 (0.62) | CYSLTR1FFAR1AKR1B1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668146-A | ANTIINFLAMMATORY AGENTS OR ANTIALLERGENS | ABBOTT LABORATORIES (US) | 1997-09-16 | — | — | US | disclosed |