Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.65 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.65 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834954 | 0.92 | CYSLTR1 (0.60) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL8799848 | 0.87 | ALOX5 (0.70) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL9459979 | 0.86 | ALOX5 (0.67) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL9459973 | 0.85 | ALOX5 (0.71) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL8645017 | 0.85 | CYSLTR1 (0.70) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL9459968 | 0.84 | ALOX5 (0.65) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL9460496 | 0.84 | ALOX5 (0.69) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL9430239 | 0.82 | ALOX5 (0.75) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL8645015 | 0.79 | CYSLTR1 (0.57) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 | |
| SCHEMBL10690965 | 0.79 | CYSLTR1 (0.76) | ALOX5ALOX5APCYSLTR1CYSLTR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |
| US-5358955-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-10-25 | — | — | US | disclosed |