Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.50 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786372 | 0.79 | TACR1 (0.51) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8785566 | 0.78 | TACR1 (0.56) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8947993 | 0.78 | DPP4 (0.71) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8785635 | 0.76 | TACR1 (0.61) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8948096 | 0.76 | TACR1 (0.54) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL5236388 | 0.75 | DPP4 (0.70) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8785003 | 0.75 | TACR1 (0.58) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8835008 | 0.74 | TACR1 (0.51) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8785449 | 0.74 | TACR1 (0.75) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8947918 | 0.73 | TACR1 (0.52) | TACR1DPP4KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |