SCHEMBL8835571

SCHEMBL8835571

Nc1ccc(P(c2ccc(N)cc2)c2ccc(N)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP3A4 P08684 7/20 0.47
ALDH1A1 P00352 7/20 0.47
TDP1 Q9NUW8 6/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 7/20 0.43
LMNA P02545 1/20 0.43
MPO P05164 1/20 0.43
CYP2C9 P11712 1/20 0.43
HTR6 P50406 1/20 0.43
ALOX15 P16050 2/20 0.42
CA6 P23280 2/20 0.42
CA14 Q9ULX7 2/20 0.42
MAPK1 P28482 2/20 0.42
ACHE P22303 1/20 0.42
CA3 P07451 1/20 0.42
THRB P10828 1/20 0.42
CASP1 P29466 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1068420 0.88 CYP3A4 (0.67) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL6141654 0.88 CYP3A4 (0.67) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL10385019 0.76 MAOA (0.68) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL320609 0.76 MEN1 (1.00) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL27981 0.76
SCHEMBL10401964 0.73 MAPT (0.50) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL65149 0.73 MEN1 (0.50) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL11916205 0.73 MEN1 (0.50) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL9319106 0.73 MEN1 (0.50) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL8384861 0.73 MAPT (0.50) MEN1MAPTKMT2ACYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020034476-A1 POROUS ORGANIC CAGE LIGAND CONTAINING P AND N AND COMPLEX CATALYST AND APPLICATION 中国科学院大连化学物理研究所 2020-02-20 WO disclosed
WO-2020034477-A1 POROUS ORGANIC CAGE LIGAND CONTAINING P AND N, PREPARATION THEREFOR AND USE THEREOF 中国科学院大连化学物理研究所 2020-02-20 WO disclosed
US-5599582-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-02-04 US disclosed
US-5582858-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-12-10 US disclosed
US-5569739-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-10-29 US disclosed
US-5326643-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-07-05 US disclosed
EP-0536606-A2 An adhesive layer in multilevel packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1993-04-14 EP disclosed
EP-0218100-B1 CONJUGATED ALKADIENE TELOMERIZATION TO ORGANO-OXYALKADIENES QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1989-11-29 EP disclosed
US-4808441-A Metal articles having corrosion-resistant epoxy coatings FORD MOTOR COMPANY (US) 1989-02-28 US disclosed
EP-0218100-A1 Conjugated alkadiene telomerization to organo-oxyalkadienes QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1987-04-15 EP disclosed