SCHEMBL65149

SCHEMBL65149

Nc1ccc([P](=O)c2ccc(N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP3A4 P08684 7/20 0.42
TDP1 Q9NUW8 7/20 0.42
ALDH1A1 P00352 7/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 7/20 0.39
MAPK1 P28482 3/20 0.39
TXNRD1 Q16881 1/20 0.39
TXNRD3 Q86VQ6 1/20 0.39
TXNRD2 Q9NNW7 1/20 0.39
LMNA P02545 1/20 0.39
MPO P05164 1/20 0.39
CYP2C9 P11712 1/20 0.39
HTR6 P50406 1/20 0.39
ALOX15 P16050 2/20 0.38
CA6 P23280 2/20 0.38
CA14 Q9ULX7 2/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8835571 0.73 MEN1 (0.57) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL320609 0.71 MEN1 (1.00) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL27981 0.71
SCHEMBL2153485 0.69 TYR (0.46) MEN1MAPTKMT2AALDH1A1MAPK1
SCHEMBL11916205 0.69 MEN1 (0.50) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL1304998 0.69 LMNA (0.50) CYP3A4ALDH1A1TSHRMAPK1LMNA
SCHEMBL10401964 0.69 MAPT (0.50) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL28648779 0.69 CYP2A6 (0.50) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL183976 0.69 ACHE (0.50) MEN1KMT2ATDP1ALDH1A1LMNA
SCHEMBL8384861 0.69 MAPT (0.50) MEN1MAPTKMT2ACYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9404199-B2 Polyurethane elastic yarn and method for producing same INVISTA NORTH AMERICA S.A.R.L. (US) 2016-08-02 US claimed
EP-0712866-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-22 EP claimed
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
US-4101487-A HEAT CURABLE AROMATIC DIAMINE-DIACID-AIAMIDE COMPOUND GENERAL ELECTRIC COMPANY (US) 1978-07-18 US claimed
US-12529166-B2 Polyurethane elastic fiber, winding body therefor, gather member and hygienic material ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-01-20 US disclosed
US-20250389056-A1 POLYURETHANE ELASTIC FIBER TORAY OPELONTEX CO LTD (JP) 2025-12-25 US disclosed
US-20250205932-A1 POLYURETHANE ELASTIC FIBER AND METHOD FOR PRODUCING SUCH TORAY OPELONTEX CO LTD (JP) 2025-06-26 US disclosed
US-20250196397-A1 POLYURETHANE ELASTIC FIBER AND METHOD FOR PRODUCING SUCH TORAY OPELONTEX CO LTD (JP) 2025-06-19 US disclosed
US-20250110406-A1 METHOD OF PRODUCING RESIST COMPOSITION PURIFIED PRODUCT, RESIST PATTERN FORMING METHOD, AND RESIST COMPOSITION PURIFIED PRODUCT TOKYO OHKA KOGYO CO LTD (JP) 2025-04-03 US disclosed
WO-2025053071-A1 POROUS FILM AND METHOD FOR PRODUCING POROUS FILM 東京応化工業株式会社 2025-03-13 WO disclosed
EP-4512945-A1 THERMOPLASTIC POLYURETHANE ELASTIC FIBER Asahi Kasei Kabushiki Kaisha (JP) 2025-02-26 EP disclosed
US-20250050269-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS PERMEABLE APPARATUS HITACHI GE VERNOVA NUCLEAR ENERGY, LTD. (JP) 2025-02-13 US disclosed
US-4101487-A HEAT CURABLE AROMATIC DIAMINE-DIACID-AIAMIDE COMPOUND GENERAL ELECTRIC COMPANY (US) 1978-07-18 US disclosed
US-4073788-A Partially imidized polyamide-acid polymers, aqueous coating compositions, coated wire and method, and partially imidized intermediate GENERAL ELECTRIC COMPANY (US) 1978-02-14 US disclosed
US-4020303-A Polyimides prepared from amine terminated prepolymers and olefin containing anhydrides GENERAL ELECTRIC COMPANY (US) 1977-04-26 US disclosed
US-4004062-A WATER SOLUBLE AROMATIC ORTHOAMIC ACID DIAMINE GENERAL ELECTRIC COMPANY (US) 1977-01-18 US disclosed
US-4003947-A REACTION PRODUCT OF AROMATIC DIAMINES AND DIANHYDRIDES; LADDER POLYMERS GENERAL ELECTRIC COMPANY (US) 1977-01-18 US disclosed
US-3975345-A ELECTROCOATING GENERAL ELECTRIC COMPANY (US) 1976-08-17 US disclosed
US-3950308-A POLYAMIDES, POLYIMIDES, POLYAMIDE-IMIDES CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed
US-3948835-A POLYAMIDE, POLYAMIDE-ACID OR POLYAMIDE-AMIDE-ACIDS CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12529166-B2 Polyurethane elastic fiber, winding body therefor, gather member and hygienic material RAD50, PCNA, DCLRE1A MEN1 634/4885MAPT 2248/4885KMT2A 4051/4885
US-20250389056-A1 POLYURETHANE ELASTIC FIBER PARG, CHERP, PUF60 MEN1 4231/4885MAPT 441/4885KMT2A 4364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.