SCHEMBL8835604

SCHEMBL8835604

[O]Cc1ccc(CCl)cc1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
TSHR P16473 1/20 0.32
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL27467661 0.86 ALDH1A1 (0.48) CA1CA2TSHRMGLL
SCHEMBL97582 0.83 CA1 (0.52) CA1CA2TSHRFAAHMGLL
SCHEMBL5358862 0.83 ALDH1A1 (0.37) CA2TSHRFAAHMGLL
SCHEMBL28372503 0.79 ALDH1A1 (0.52) CA1CA2
SCHEMBL8835987 0.77 ALDH1A1 (0.38) CA1CA2TSHR
SCHEMBL50384 0.75
SCHEMBL7182298 0.75
SCHEMBL18713263 0.75 CA1 (0.42) CA1CA2
SCHEMBL308301 0.75
SCHEMBL5885169 0.73 CYP3A4 (0.47) CA1CA2TSHRFAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5633268-A FUNGICIDES, INSECTICIDES, PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-05-27 US disclosed