SCHEMBL50384

SCHEMBL50384

[O]Cc1ccc(Cl)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14855317 0.92 MAOB (0.52)
SCHEMBL5358862 0.83 ALDH1A1 (0.37)
SCHEMBL2657239 0.79 TAAR1 (0.59)
SCHEMBL696213 0.77 TAAR1 (0.56)
SCHEMBL8835604 0.75 CA1 (0.48)
SCHEMBL3815244 0.75
SCHEMBL15351609 0.75 CYP2A6 (0.50)
SCHEMBL2135113 0.73 TAAR1 (0.68)
SCHEMBL1106684 0.73 IDO1 (0.58)
SCHEMBL15351870 0.73 CYP2A6 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1723 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 US claimed
CN-115894486-B Hydrogenated pyridoquinazoline compound, composition and application thereof 北京赛特明强医药科技有限公司 2024-02-09 CN claimed
EP-4313943-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-02-07 EP claimed
CN-111655685-B Thiophene derivative and use thereof 藤本株式会社 2023-11-17 CN claimed
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 CN claimed
US-20230277505-A1 DIARYL AND ARYLHETEROARYL UREA DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO ARENA PHARM INC (US) 2023-09-07 US claimed
CN-115572278-B Genipin derivative and preparation method and application thereof 北京志道生物科技有限公司 2023-09-01 CN claimed
EP-3744719-B1 THIOPHENE DERIVATIVE AND USE THEREOF FUJIMOTO CO LTD (JP) 2023-06-07 EP claimed
CN-115894486-A Hydrogenated pyridoquinazoline compound, composition and application thereof 北京赛特明强医药科技有限公司 2023-04-04 CN claimed
CN-115894455-A Quinazoline compound, composition and application thereof 北京赛特明强医药科技有限公司 2023-04-04 CN claimed
US-4427437-A PLANT GROWTH REGULATORS ICI AUSTRALIA LIMITED (AU) 1984-01-24 US claimed
EP-0008192-B1 BIS(PYRIMIDYLOXY)-, BIS(PYRIMIDYLTHIO)-, AND PYRIMIDYLOXY-PYRIMIDYLTHIO-BENZENE DERIVATIVES AND THEIR USE AS HERBICIDES, AND PROCESSES OF PREPARING THEM ICI AUSTRALIA LIMITED (AU) 1983-10-12 EP claimed
US-4329460-A ANTICANCER AGENTS, ANTIVIRAL AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-05-11 US claimed
EP-0002774-B1 PROCESS FOR ACYLATING 7AMINOCEPHEM DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1981-09-23 EP claimed
US-4248619-A Bis[pyrimidyloxy(thio)]benzene derivatives ICI AUSTRALIA LIMITED (AU) 1981-02-03 US claimed
EP-0008192-A1 Bis(pyrimidyloxy)-, bis(pyrimidylthio)-, and pyrimidyloxy-pyrimidylthio-benzene derivatives and their use as herbicides, and processes of preparing them ICI AUSTRALIA LIMITED (AU) 1980-02-20 EP claimed
US-4182776-A Method of treating lipidemia with aryloxyalkylaminobenzoic acids and esters AMERICAN CYANAMID COMPANY (US) 1980-01-08 US claimed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP claimed
US-4148625-A Tetrahydroisophthalimide compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-04-10 US claimed
US-3941799-A 6-Substituted-11b-phenyl-3, 11bH-oxazirino[2,3-d]-s-triazol[4,3-a][1,4]benzodiazepines CIBA-GEIGY CORPORATION (US) 1976-03-02 US claimed