SCHEMBL8835623

SCHEMBL8835623

C=C(C)C(=O)OC(O)(CC)CCO

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35
TSHR P16473 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3463417 0.84 TSHR (0.44) ALDH1A1THRBTSHR
SCHEMBL28427167 0.82 TSHR (0.47) ALDH1A1TSHR
SCHEMBL19019778 0.79 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL15219177 0.78 TSHR (0.37) ALDH1A1THRBTSHR
SCHEMBL12941443 0.78 TSHR (0.37) ALDH1A1THRBTSHR
SCHEMBL2276104 0.76 ALDH1A1 (0.34) ALDH1A1THRBTSHR
SCHEMBL12941441 0.75 TSHR (0.36) ALDH1A1THRBTSHR
SCHEMBL6924019 0.75 ALDH1A1 (0.39) ALDH1A1THRBTSHR
SCHEMBL8475055 0.75 ALOX15 (0.34)
SCHEMBL1397630 0.74 ALDH1A1 (0.35) ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691417-A HYDROXYALKYL ACRYLATE INTERPOLYMERS, ISOCYANATES, STYRENE-FREE HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-11-25 US disclosed