Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 6/20 | 0.33 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8836779 | 0.94 | DAO (0.39) | DAOALDH1A1NPSR1TRPV4CYP11B1 | |
| SCHEMBL8836848 | 0.93 | TSHR (0.41) | DAOMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8836518 | 0.92 | DAO (0.41) | DAOTRPV4CYP11B1CYP11B2KCNJ1 | |
| SCHEMBL8473158 | 0.88 | ALDH1A1 (0.41) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL7735008 | 0.87 | TSHR (0.43) | DAOMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8474034 | 0.85 | RARB (0.33) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL8146455 | 0.82 | DAO (0.49) | DAOMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8470743 | 0.81 | TSHR (0.37) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL8473480 | 0.81 | DAO (0.40) | DAO | |
| SCHEMBL8470777 | 0.81 | TSHR (0.50) | DAOKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |