SCHEMBL8836136

SCHEMBL8836136

NO[C@H]([C@H](O)CO)[C@@H](O)C=O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.37
MPI P34949 1/20 0.35
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2635114 0.88 AKR1B1 (0.34) AKR1B1MPILMNAL3MBTL1
SCHEMBL4288124 0.88 AKR1B1 (0.34) AKR1B1MPILMNAL3MBTL1
SCHEMBL1764018 0.88 AKR1B1 (0.34) AKR1B1MPILMNAL3MBTL1
SCHEMBL10713437 0.88 LMNA (0.39) AKR1B1MPILMNAL3MBTL1
SCHEMBL770242 0.88 LMNA (0.39) AKR1B1MPILMNAL3MBTL1
SCHEMBL2635169 0.88 LMNA (0.39) AKR1B1MPILMNAL3MBTL1
SCHEMBL4310076 0.78 AKR1B1 (0.37) AKR1B1MPILMNAL3MBTL1
SCHEMBL3142523 0.78 AKR1B1 (0.37) AKR1B1MPILMNAL3MBTL1
SCHEMBL5453628 0.78 AKR1B1 (0.37) AKR1B1MPILMNAL3MBTL1
SCHEMBL22692162 0.78 AKR1B1 (0.37) AKR1B1MPILMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025058295-A1 GLOMERULUS-ON-CHIP AND USE THEREOF 서울대학교병원 2025-03-20 WO claimed
US-4169197-A ANTIBIOTICS THE UPJOHN COMPANY (US) 1979-09-25 US claimed
WO-2025058295-A1 GLOMERULUS-ON-CHIP AND USE THEREOF 서울대학교병원 2025-03-20 WO disclosed
CN-1051921-C Methods of inhibiting imperfect tissue repair LILLY CO ELI (US) 2000-05-03 CN disclosed
US-5686467-A 2-PHENYL-3-AROYLBENZOTHIOPHENES ELI LILLY AND COMPANY (US) 1997-11-11 US disclosed
US-5574047-A Methods of inhibiting imperfect tissue repair ELI LILLY AND COMPANY (US) 1996-11-12 US disclosed
CN-1109330-A Methods of inhibiting imperfect tissue repair LILLY CO ELI (US) 1995-10-04 CN disclosed
EP-0664122-A1 Inhibition of imperfect tissue repair ELI LILLY AND COMPANY (US) 1995-07-26 EP disclosed